MK is overexpressed in most of human malignant tumors, such as carcinomas of the oral cavity [116], esophagus [117], stomach [117], colon [117], liver [117], pancreas [118], lung [119], urinary bladder [120], prostate [121], breast [122], uterus [123, 124] and ovary [125], osteosarcoma [126], soft tissue sarcoma [127], neuroblastoma [128], astrocytoma [129 ], meningioma [130], and acute lymphoblastic leukemia [131]. This evidence concerns the gene MDK and cancer.