Although not supported by incontestable evidence, it is possible that patients with runs of nonsustained ventricular tachycardia on Holter/exercise testing, and asymptomatic or mildly symptomatic left ventricular dysfunction on echocardiography, derive some benefit from combined therapy with an angiotensin-converting enzyme inhibitor and amiodarone. This evidence concerns the gene ACE and ventricular tachycardia.