With data from 191 healthy blood donors whose MDM ranked in the bottom quartile with lowest (n = 95 donors) or top quartile with highest (n = 96 donors) Gag p24 production 14 days post infection with HIV-1 [39] (Table 1), we found strongest associations for SNPs in the genes PDE8A (rs2304418, p = 2.4×10−6 and rs12909130, p = 8.3×10−6), UBR7 (rs2905, p = 7.0×10−6), MOAP1 (rs1046099, p = 9.9×10−6 and rs1270629, p = 1.09×10−5), DYRK1A (rs12483205, p = 2.2×10−5) and SPOCK3 (rs17519417, p = 2.5×10−5) (Figure 1, Table S1). The gene discussed is PDE8A; the disease is infection.