Nitric oxide, which is formed by the constitutive isoforms of NO synthase, endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS), plays an important roles in the regulation of cerebral blood flow and cell viability and in the protection of nerve cells or fibers against pathogenic factors associated with neurological disorders [3]. This evidence concerns the gene NOS3 and nervous system disorder.