Astressin-B (5 μg/mouse) injected ip for 5 days reversed alopecia but did not modify the elevated plasma corticosterone levels in CRF-OE mice at any of the days monitored, i.e, days 1, 3, 7 and 14 after the last ip astressin-B injection (Fig. 4A). The gene discussed is PPIB; the disease is alopecia.