This was done in two stages, 20 SNPs were typed and analysed first and, based on these and earlier results, 35 more variants were added, particularly in the genes TMTC1, HMGA2 (OMIM*600698) and PAWR (OMIM*601936), which displayed the strongest association with PCa (Tables S1 and S4). The gene discussed is TMTC1; the disease is posterior cortical atrophy.