The mRNA levels of 9 of the 20 selected genes (i.e. NDC80, BUB1, BUB1B, CCNB1, TACC3, TPX2, CCNA2, CDC2 and CDC20) was significantly increased in the benign breast tumors as compared to the normal breast tissues (Table 3). Here, TPX2 is linked to breast benign neoplasm.