In conclusion, our results demonstrate that P1 (MAGE-A4286–294, KVLEHVVRV) and P3 (MAGE-A4272–280, FLWGPRALA) derived from MAGE-A4 are HLA-A*0201-restricted CTL epitopes, which can be endogenously presented to the surface of HLA-A*0201+MAGE-A4+ tumor cells. This evidence concerns the gene MAGEA4 and neoplasm.