In an animal model of sepsis, delayed administration of fetuin-A (20–100 mg/kg), beginning 24 h after the onset of sepsis and followed by an additional dose at 48 h post CLP, dose-dependently and significantly increased long-term animal survival rates from 45% to 90% (P<0.05, Fig. 3B, bottom panel). Here, AHSG is linked to Sepsis.