Consistent with our 2D-DIGE proteomic data, the validation by western results demonstrated overexpression of eIF4A3, DDAH1, ARG2, Prdx3, and Prdx4 in significantly high percentage of PCa tissues compared to corresponding benign samples (% of tumors showing differential expression of each protein described in results section). Here, PRDX3 is linked to posterior cortical atrophy.