TP53 and neoplasm: The p53-mediated regulation of miR-125b is consistent with recent data showing that miR-125 served as a tumor suppressor microRNA in tumor cells [22] and that miR-125 is upregulated along with the p53 targets miR-34a-c, in K562 cells in response to cisplatin [23], a p53-dependent apoptotic inducer [24].