To determine the impact of IL-22 on bacterial clearance during a mucosal LM infection, B6 and IL-22 KO mice were i.g. infected with LM/strepr and spleens, livers, and intestines were harvested at days 1 and 3 p.i. There were no LM CFU differences between B6 and IL-22 KO mice at days 1 and 3 p.i. (data not shown), again suggesting that IL-22 is not required for clearance of LM during mucosal infection. Here, IL22 is linked to lymphangioma.