With respect to individual components of MetS (Table 3), HMW-adiponectin was strongly associated with a decreased risk of hypertriglyceridemia (OR in the highest quartile  = 0.26, 95%CI 0.16∼0.42, Ptrend<.0001) and low HDL-C (OR in the highest quartile  = 0.22, 95%CI 0.14∼0.35, Ptrend<.0001), while marginally associated with central obesity (OR in the highest quartile  = 0.49, 95%CI 0.25∼0.97, Ptrend = 0.06) in the FMI-adjusted model. The gene discussed is ADIPOQ; the disease is Abdominal obesity.