Replacing BMI with FMI (Model 4) did not substantially change the significant associations for both HMW-adiponectin and sOB-R (ORs in the highest quartile were 0.30, 95%CI 0.18∼0.50, Ptrend<.0001 and 0.61, 95%CI 0.36∼1.02, Ptrend = 0.02, accordingly); but abolished the significance between leptin and the risk of MetS (Ptrend = 0.23). This evidence concerns the gene LEP and metabolic syndrome.