4. Ambulatory exacerbation identified by qualifying drug therapy: a pharmacy claim for the following oral antibiotics commonly used for respiratory infections amoxicillin, beta-lactamase inhibitors, second or third-generation cephalosporins, macrolides, or doxycycline) or a claim for systemic steroids (oral, intramuscular, or intravenous). This evidence concerns the gene LACTB and respiratory tract infectious disorder.