DotScanTM CRC antibody microarrays and fluorescence multiplexing were used to profile the cells, and the CD3+ subset showed differential expression of HLA-DR, TCRα/β, CD49d, CD52, CD49e, CD5, CD95, CD28, CD38 and CD71 in descending order of difference [21]. Here, CD28 is linked to colorectal carcinoma.