The authors attribute their findings to the proposed non-genotoxic action of Nutlin-3, however Nutlin-3-induced phosphorylation of p53 at Ser15 has since been reported in both B-cell chronic lymphocytic leukaemia (B-CLL) and mantle cell lymphoma (MCL) models [23]. The gene discussed is TP53; the disease is B-cell chronic lymphocytic leukemia.