DMRT1 and teratoma: The DBP-induced alteration in DMRT1 expression is therefore of potential relevance to the origins/causes of human TGCC, although the pattern of change induced (delayed switching off and on) cannot be related in a straightforward manner to the mouse studies in which it was loss of DMRT1 expression that predisposed to teratoma formation (Krentz et al., 2009).