Following on the heels of this discovery, the Boon group identified the first human tumor-associated T-cell-defined antigen, MAGE-1 (Melanoma Antigen-1, subsequently renamed MAGE-A1) by screening target cells transfected with the cDNA library of a tumor line using autologous tumor reactive antigen-specific CTL. This evidence concerns the gene SLC45A2 and neoplasm.