Conversely, ALK− ALCLs were found to overexpress CCR7, CNTFR, IL22, and IL21. Overall, this study strongly supported the concept that ALK+ and ALK− ALCL are different entities but did not provide novel information as far as the molecular pathogenesis of ALK− ALCL was concerned. This evidence concerns the gene CNTFR and anaplastic large cell lymphoma.