MYC and neoplasm: We then analyzed c-MYC mRNA expression in formalin-fixed paraffin-embedded tumor samples (FFPE) from well-documented patients with postoperative residual tumor mass treated within the prospective multi-center studies HIT'91 and HIT 2000 and compared c-MYC mRNA expression with response to radio- and chemotherapy, as determined by neuroradiological imaging.