This study evaluated 8 of these genes (IL4, IL13, TNF-α, HLA-DRB1, HLA-DQB1, FCER1B/MS4A2, CD14, ADAM33) as well as 3 glutathione-s-transferase genes (GSTM1, GSTP1, and GSTT1) for association with asthma/allergy among urban-residing African Americans. This evidence concerns the gene IL4 and allergic disease.