Expression levels of eIF4E, 4E-BP1, 4E-BP2 and Thr37/Thr46 phosphorylated 4E-BP1 (phospho-4E-BP1) within tumour cells were determined semi-quantitatively in matched pre- and post-treatment tumour samples from 22 patients using immunohistochemistry. The gene discussed is EIF4EBP1; the disease is neoplasm.