HDGFL2 and malaria: First, specificity may be reduced by the persistence of HRP2 for up to 5 weeks following clearance of parasites and this may be a particular concern in patients who are frequently infected or who have recently taken antimalarial drugs, both of which may be more likely in hospitalised children in malaria-endemic areas (Wongsrichanalai et al. 1999; Swarthout et al. 2007).