SPT can be readily diagnosed by routine histologic examination, but accuracy of diagnosis may be improved with the help of immunohistochemical staining because such tumours are typically negative for cytokeratin, pancreatic enzyme markers, and endocrine markers but positive for vimentin, CD 10, CD 56, and alpha-antitrypsin [3–7, 9, 10]. The gene discussed is VIM; the disease is neoplasm.