INS and Hyperglycemia: The aim of this study was to investigate whether insulin glargine is equally effective if administered in the morning or at bedtime in combination with preprandial insulin analogue on glycemic control and nocturnal hypo/hyperglycemia, based on blood glucose values from 24 hour glucose monitorization system (CGMS) (Medtronic Minimed [Northridge CA]) on the 12th week when the metabolic control had been stabilized.