FOXO1 and endometrial cancer: Recently, our group has followed up on these observations [37] and could show that progesterone efficiently inhibited the expression of a Wnt/β-catenin signaling reporter plasmid (TOP/FOPflash) in the Ishikawa endometrial cancer cell line by induction of the Wnt/β-catenin inhibitors DKK1 [66] and FOXO1 [38].