Acetyl-coA carboxylase (ACC) and fatty acid synthase (FAS)are upregulated in many cancers and also play a role in tumorigenesis [24,25].FAS synthesizes long chain fatty acids (e.g. palmitate) from malonyl-coA and NAPDH.Regulation by signaling pathways, such as the PI3K/AKT/mTOR pathway also modulatelipid synthesis. This evidence concerns the gene FAS and cancer.