ICC results always yielded unspecific perinuclear staining of cells from ovine origin whereas in WB, monoclonal antibodies to human MR failed to detect mouse MR (likely due to the lack of cross-reactivity), whereas the polyclonal serum against human MR detected only murine MR on the CHO-MR cell surface which expression has been previously shown [24]. The gene discussed is NR3C2; the disease is intrahepatic cholangiocarcinoma.