CXCL8 and ischemic stroke: In this regard, we have previously reported IL-8 serum levels after ischemic stroke [20] and other authors have shown that patients with ischemic stroke had high numbers of IL-8 mRNA expressing blood-mononuclear cells correlated with protein plasma level [21] and that high plasma level of IL-8 during the acute phase of ischemic stroke are maintained elevated at one week when compared to controls [22].