Sharing a common genetic origin, the hereditary corneal dystrophies linked to chromosome 5q31 and TGFBI include Reis-Bücklers corneal dystrophy (RBCD, also called Granular corneal dystrophy, type 3 [GCD3]), Thiel-Behnke corneal dystrophy (TBCD), Classic Lattice corneal dystrophy (LCD1), Granular corneal dystrophy, type 1 (GCD1) and type 2 (GCD2) [8,9]. This evidence concerns the gene TGFBI and Reis-Bucklers corneal dystrophy.