Identified genes responsible for corneal dystrophies include transforming growth factor-beta-induced (TGFBI), carbohydrate sulfotransferase 6 (CHST6), gelsolin (GSN), keratin 3 (KRT3), keratin 12 (KRT12), and chromosome 1, surface marker 1 (M1S1), with TGFBI mutations in human autosomal dominant corneal dystrophies being the most commonly observed. This evidence concerns the gene KRT12 and corneal dystrophy.