To date we have identified 10 novel CLL risk loci at 2q13 (rs17483466), 2q37.1 (rs13397985, SP140), 6p25.3 (rs872071, IRF4), 11q24.1 (rs735665), 15q23 (rs7176508), and 19q13.32 (rs11083846, PRKD2) 2q37.3 (rs757978), 8q24.21 (rs2456449), 15q21.3 (rs7169431) and 16q24.1 (rs305061, IRF8) [8, 10] and four risk loci for ALL at 7p12.2 (IKZF1, rs4132601), 10q21.2 (ARID5B, rs7089424) and 14q11.2 (CEBPE, rs2239633) [9, 11, 12]. This evidence concerns the gene IRF8 and B-cell chronic lymphocytic leukemia.