WNT5A and Parkinson disease: It is also known that treatment of prenatal DA progenitors with inhibitors of the β-catenin kinase GSK3β enhances DA neurogenesis [29] and that transplantation of rodent fetal neural stem cells treated with Wnt5a results in enhanced survival, differentiation and functional integration of stem cell-derived DA neurons in an animal model of Parkinson's disease [22].