CD4 and AIDS: While the HIV controllers had significantly higher median CD4+ T cell counts than the ART-suppressed (683 vs. 449 cells/mm3, P<0.001) and the non-controllers (683 vs. 251 cells/mm3, P<0.001), 9 HIV controllers (17%) had CD4+ T cell counts below 350 cells/mm3 and 4 (7%) met the clinical definition of AIDS (one with Kaposi's sarcoma and three with CD4+ T cell counts persistently <200 cells/mm3) despite maintaining viral suppression in the absence of therapy.