Infectious prion diseases such as Creutzfeldt Jakob disease (CJD) and other related human disorders, chronic wasting disease (CWD), bovine spongiform encephalopathy (BSE), and scrapie are associated with the conversion of a host-encoded glycoprotein (PrPC) into a misfolded conformer, PrPSc[3]. This evidence concerns the gene PRNP and Creutzfeldt Jacob disease.