In BC, we have reported that miR-133a had a critical role in regulating oncogenic FSCN1, LASP1, and GSTP1 (Uchida et al, 2010; Chiyomaru et al, 2010a, 2010b) and have demonstrated for the first time that LASP1 was the target of miR-1/miR-133a cluster (Chiyomaru et al, 2010b). The gene discussed is LASP1; the disease is breast cancer.