Moreover, using percentage ER-positivity, grading, diameter of the tumor, and Rab27B score as variables in a logistic regression model, only Rab27B score was significantly linked to lymph node metastasis (Odds Ratio = 10.1; 95% Confidence Interval = 1.67 to 60.93; P = 0.01) (Clinical data are available in Supplementary Table 2 in [3]). This evidence concerns the gene RAB27B and metastatic malignant neoplasm in the lymph nodes.