MYCN and neuroblastoma: To determine whether expression of B-MYB is required for proliferation of MYCN-amplified neuroblastoma cells, three MYCN-amplified (LAN-1, GI-LIN, IMR-32) and two MYCN non amplified (GI-MEN, ACN) cell lines were infected with lentiviruses carrying B-MYB, or scrambled shRNAs, and expressing GFP.