PTEN and neurodevelopmental disorder: Furthermore, FMRP interacts with several proteins that have been identified as potential candidate genes underlying a number of neurodevelopmental disorders, such as the neuroligin family, neurorexin 1, SH3 and multiple ankyrin repeat domains (SHANK 3), phosphatase and tensin homolog (PTEN), mammalian target of rapamycin (mTOR), PSD95, Wnt7a and Arc (Arg 3.1) [7,14-20].