SLC6A4 and obesity due to melanocortin 4 receptor deficiency: This prompted us to preliminary assess the equilibrium-binding parameters of SERT and TSPO proteins, either in brain or high expression peripheral tissues, circulating platelets and kidneys, of ob/ob mice: to our knowledge, this is the first study that simultaneously evaluates SERT and TSPO expression in distinct anatomical district of a rodent genetic model of obesity.