Also called Anderson-Fabry disease, Fabry’s is caused by mutations in the GLA gene, which encodes alpha-galactosidase A, resulting in accumulation of glycosphingolipids, specifically globotria-oslyceramide, within the lysosomes.1 This accumulation leads to cellular dysfunction, particularly in the endothelium, resulting in hypo-perfusion of tissues and further inflammation. This evidence concerns the gene GLA and Fabry disease.