CD4 and Schnyder corneal dystrophy: In contrast to the visceral adipose, there was a significant increase in CD3+GFP+ and CD4+GFP+ cells in the splenic response to HFD (Figure 3C, p<0.0008 & p<0.005 respectively vs. SCD) with a concominant decrease in total splenic CD4+ T cells (p<0.005).