However, psychotic schizophrenia-like symptoms have also been noted amongst Huntington's disease patients [31], [32], [33] consistent with the interaction of huntingtin with proteins from other schizophrenia-associated genes such as PCM1, PDE4B and DPYSL2 [11]–[13], [34]–[36]. This evidence concerns the gene DPYSL2 and Huntington disease.