In contrast, increased transcript levels of hyaluronan/CD44, which is normally expressed by astrocyte progenitors [44] and frequently overexpressed in TSCs derived from solid tumors (including gliomas) [45], were observed in all the tumor cultures assayed but not in the human fetal neural stem cells, as compared to adult cortical tissues (Figure 4B). The gene discussed is CD44; the disease is central nervous system cancer.