RNLS and heart failure: We also analyzed the correlation between renalase expression in kidney and plasma levels of norepinephrine (r = −0.485, p = 0.110) or the correlation between plasma concentration of renalase and norepinephrine (r = −0.532, p = 0.075) at 4 weeks following LAD ligation, although which showed no statistical significance, the tendency of the higher renalase, the lower norepinephrine did exist in heart failure rats (data not shown).