We again compared the samples based on VDAC1 expression and found the 6-gene signature was conserved in 8 of these cell lines, namely UACC62 and SK_MEL2 (melanoma), SF295 and SF539 (CNS), A498 and SNC12C (renal), H23 and HOP62 (NSCLC). This evidence concerns the gene VDAC1 and melanoma.