The status (amplified, deleted or normal) of the 11 genes (MED1, STARD3, GRB7, THRA, RARA, TOP2A, IGFBP4, CCR7, KRT20, KRT19 and GAS) evaluated in the 86 HER2-positive cancer samples is summarized in Table 3. This evidence concerns the gene IGFBP4 and cancer.