So far, many HCC-related oncogenes, including AFP, RAS, c-FOS, c-JUN, RHO, TGF-a, HGF, CerbB2, HER-2, HER-2/neu, NEU, NGL, MDM2, MMP, and IGF-⫽ , have been found. The gene discussed is ERBB2; the disease is hepatocellular carcinoma.