Meanwhile, the TMPRSS2-ERG translocation, which has been found to occur with regular frequency in prostate carcinomas, appears to be associated with HDAC expression and is thus linked with sensitivity to HDAC inhibitors (Tomlins et al, 2005; Iljin et al, 2006; Bjorkman et al, 2008). Here, TMPRSS2 is linked to prostate carcinoma.