VEGFA and neoplasm: Tumour angiogenesis has become a prominent drug target for cancer therapy (Carmeliet, 2005) and agents designed to target the vascular endothelial growth factor (VEGF) family and the fibroblast growth factor (FGF) family, along with their corresponding receptor tyrosine kinases, have received considerable attention (Sparano et al, 2004; Folkman, 2007).