CXCL1 and neoplasm: Although CXCL1 expression has previously been detected in CRC epithelium (Cuenca et al, 1992; Baier et al, 2005; Wen et al, 2006), our analysis showed an additional correlation between CXCL1 and the expression of its biological target, the CXCR2 receptor within the tumour samples (P<0.001).